IOGP-IPIECA have previously developed four publications to assist the oil and gas industry in managing fatigue. This publication supersedes the preceding documents by bringing together and updating all the elements of the previous publications – Report 392 - Fatigue Management in the workplace, Report 488 - Performance indicators for fatigue risk management systems, Report 492 - Assessing risks from operator fatigue, and Report 536 - Fatigue in fly-in, fly-out operations – into one resource to help organisations to implement, monitor, and manage fatigue risk management systems. This report is supplemented by three additional packages – Report 626-1, Fatigue Info Sheets, Report 626-2 – Biomathematical references list, and 626-3 – Supplementary checklists and tools.